The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 09, 2003
Filed:
Nov. 20, 2001
Applicant:
Inventors:
Vladimir Artymovich Pasechnik, Salisbury, GB;
Allen Douglas Glen Roberts, Southampton, GB;
Richard James Sharp, Salisbury, GB;
Assignee:
Health Protection Agency, Salisbury, GB;
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 3/964 ; A61K 3/940 ; C12N 1/570 ; C12N 1/575 ; C12N 1/580 ;
U.S. Cl.
CPC ...
A61K 3/964 ; A61K 3/940 ; C12N 1/570 ; C12N 1/575 ; C12N 1/580 ;
Abstract
An agent for combating an intracellular microbial infection comprises a phage component and, associated therewith, a targeting moiety which directs the agent to a target cell and initiates delivery of the phage into the target cell. Once inside the target cell, the phage causes lysis of a microorganism residing within the target cell. A mycobacteriophage is combined with a targeting moiety of transferrin. Compositions comprising the agent, methods of preparing said agent, and use of said agent for combating intracellular infections are also provided.