The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 09, 2003
Filed:
Dec. 08, 2000
Applicant:
Inventors:
Sylvie Laquerre, Walnut Creek, CA (US);
Terry Hermiston, Corte Madera, CA (US);
Assignee:
Onyx Pharmaceuticals, Inc., Richmond, CA (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A01N 6/300 ; C12P 2/106 ; C12N 1/566 ; C12N 1/500 ; C12N 5/00 ;
U.S. Cl.
CPC ...
A01N 6/300 ; C12P 2/106 ; C12N 1/566 ; C12N 1/500 ; C12N 5/00 ;
Abstract
The present invention relates to pharmaceutical compositions, kits, and methods of use thereof, comprising, a mutant human herpes simplex-type 1 virus, which is cytopathic to susceptible hyperproliferative cells, such as neoplastic cells. Preferably, the virus does not produce a fully functionally active wild-type ICP0 polypeptide coded for the IE gene 1.