The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 02, 2003

Filed:

Sep. 04, 1997
Applicant:
Inventors:

Raju Kucherlapati, Darien, CT (US);

Aya Jakobovits, Menlo Park, CA (US);

Sue Klapholz, Stanford, CA (US);

Daniel G. Brenner, San Mateo, CA (US);

Daniel J. Capon, Hillsborough, CA (US);

Assignee:

Abgenix, Inc., Fremont, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12P 2/100 ; A01K 6/7027 ; C12N 1/563 ;
U.S. Cl.
CPC ...
C12P 2/100 ; A01K 6/7027 ; C12N 1/563 ;
Abstract

Antibodies with fully human variable regions against a specific antigen can be prepared by administering the antigen to a transgenic animal which has been modified to produce such antibodies in response to antigenic challenge, but whose endogenous loci have been disabled. Various subsequent manipulations can be performed to obtain either antibodies per se or analogs thereof.


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