The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 02, 2003

Filed:

Mar. 08, 2001
Applicant:
Inventors:

Anand C. Burman, Ghaziabad, IN;

Rama Mukherjee, Ghaziabad, IN;

Honey Bala, Ghaziabad, IN;

Dhiraj Khattar, Ghaziabad, IN;

Assignee:

Dabur Research Foundation, Uttar Pradesh, IN;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 3/120 ; A61K 3/115 ; A61K 3/121 ; A61K 3/156 ;
U.S. Cl.
CPC ...
A61K 3/120 ; A61K 3/115 ; A61K 3/121 ; A61K 3/156 ;
Abstract

The present invention provides compositions and methods for the solubilization of poorly soluble drugs such as triterpenes like betulinic acid and/its derivatives in pharmaceutically acceptable liquid vehicles that avoid use of potentially toxic solvents that are often used for the solubilization of poorly soluble drugs. In the compositions of this invention the drugs remain physically and chemically stable and can be administered intravascularly without undue toxicity from undissolved drug and/or from the solvent vehicles at a drug dose meant to be effective to exhibit clinically significant anticancer activity.


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