The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 02, 2003
Filed:
Mar. 14, 2001
Samuel J. Danishefsky, Englewood, NJ (US);
Peter Bertinato, Old Lyme, CT (US);
Dai-Shi Su, New York, NY (US);
Dang Fang Meng, New York, NY (US);
Ting-Chao Chou, Paramus, NJ (US);
Ted Kamenecka, New York, NY (US);
Erik J. Sorensen, San Diego, CA (US);
Aaron Balog, New York, NY (US);
Kenneth A. Savin, New York, NY (US);
Sloan-Kettering Institute for Cancer Research, New York, NY (US);
Abstract
The present invention provides convergent processes for preparing epothilone A and B, desoxyepothilones A and B, and analogues thereof. Also provided are analogues related to epothilone A and B and intermediates useful for preparing same. The present invention further provides novel compositions based on analogues of the epothilones and methods for the treatment of cancer and cancer which has developed a multidrug-resistant phenotype.