The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Dec. 02, 2003

Filed:

Feb. 07, 2000
Applicant:
Inventors:

W. Michael Kavanaugh, Mill Valley, CA (US);

Marcus Ballinger, Burlingame, CA (US);

Assignee:

Chiron Corporation, Emeryville, CA (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12N 1/585 ; C12N 1/563 ; C07H 2/104 ; C07K 1/400 ; A61K 3/802 ;
U.S. Cl.
CPC ...
C12N 1/585 ; C12N 1/563 ; C07H 2/104 ; C07K 1/400 ; A61K 3/802 ;
Abstract

The invention relates to compositions and methods for inhibiting cell proliferation, especially angiogenesis. The invention specifically relates to fusions of the extracellular domain of a fibroblast growth factor receptor (FGFR) with a heterologous oligomerization domain, such as that contained in an immunoglobulin, to provide potent FGFR antagonists.


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