The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Dec. 02, 2003
Filed:
Jul. 05, 2001
Richard H. J. Begent, London, GB;
Kerry Chester, London, GB;
Nigel P. Minton, Wiltshire, GB;
Anthony R. Rees, Bath, GB;
Surinder K. Sharma, London, GB;
Daniel I. R. Spencer, Hertfordshire, GB;
Cancer Research Technology Limited, London, GB;
Abstract
The invention relates to improvements relating to cancer therapy based on the identification of a number of regions of CPG2 which contain epitopes which appear to be involved in the production of a host immune response and which may be modified to alter the immunogenicity in patients. Production of fusions of CPG2 with an antibody, where the CPG2 protein has been tagged provides a CPG2 protein which has reduced immunogenicity. By using partially glycosylated enzyme obtainable by expression, the efficacy of antibody-CPG2 fusions is enhanced.