The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 25, 2003

Filed:

Aug. 16, 2000
Applicant:
Inventors:

Robert Newcomb, Palo Alto, CA (US);

Andrew L. Palma, San Ramon, CA (US);

Balazs G. Szoke, Palo Alto, CA (US);

Katalin Tarczy-Hornoch, Berkeley, CA (US);

William F. Hopkins, Mountain View, CA (US);

Ruth L. Cong, Fremont, CA (US);

George P. Miljanich, Redwood City, CA (US);

Robin Dean, Mountain View, CA (US);

Laszlo Nadasdi, Walnut Creek, CA (US);

Laszlo Urge, Berkeley, CA (US);

Stephen Scott Bowersox, Menlo Park, CA (US);

Assignee:

Elan Pharmaceuticals, Inc., South San Francisco, CA (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07H 2/102 ; C07H 2/104 ; A61K 3/802 ; A61K 3/817 ;
U.S. Cl.
CPC ...
C07H 2/102 ; C07H 2/104 ; A61K 3/802 ; A61K 3/817 ;
Abstract

A novel class of peptides selectively block class E voltage-gated calcium channels. The class is exemplified by HG peptides such as HG-1, which is isolated from the venom-producing cells of the tarantula Hysterocrates gigas. Also disclosed are methods of producing blocking class E channels using the peptides. HG peptides have utility, for example, in inhibiting oxytocin release and for use as anticonvulsants.


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