The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 25, 2003

Filed:

Jul. 28, 2000
Applicant:
Inventors:

Wayne R. Spevak, Albany, CA (US);

Songyuan Shi, Fremont, CA (US);

Prasad V. V. S. V. Manchem, South San Francisco, CA (US);

Michael R. Kozlowski, Palo Alto, CA (US);

Steven R. Schow, Redwood Shores, CA (US);

Robert T. Lum, Palo Alto, CA (US);

Louise Robinson, San Carlos, CA (US);

Jeong Weon Park, Emeryville, CA (US);

Assignee:

Telik, Inc., Palo Alto, CA (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 3/150 ; A61K 3/1545 ; C07D / ; C07D / ; C07C / ;
U.S. Cl.
CPC ...
A61K 3/150 ; A61K 3/1545 ; C07D / ; C07D / ; C07C / ;
Abstract

Methods for treating conditions associated with hyperglycemia, especially Type II diabetes, with novel naphthylsulfonic acids and related compounds. These compounds, as single stereoisomers or mixtures of stereoisomers, or their pharmaceutically acceptable salts, are useful in methods of stimulating the kinase activity of the insulin receptor, enhancing the activation of the insulin receptor by insulin, and stimulating the uptake of glucose into cells. A variety of antidiabetic compounds and pharmaceutical compositions comprising the antidiabetic compounds are also disclosed.


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