The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 25, 2003

Filed:

Oct. 11, 2001
Applicant:
Inventors:

Jean-Marc Roch, Salt Lake City, UT (US);

Paul L. Bartel, Salt Lake City, UT (US);

Karen Heichman, Salt Lake City, UT (US);

Kimberly Mauck, Sandy, UT (US);

Max Dufford, Salt Lake City, UT (US);

Assignee:

Myriad Genetics, Inc., Salt Lake City, UT (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12N 1/500 ; C12N 1/563 ; C12N 1/585 ; C12N 9/00 ; C07H 2/104 ;
U.S. Cl.
CPC ...
C12N 1/500 ; C12N 1/563 ; C12N 1/585 ; C12N 9/00 ; C07H 2/104 ;
Abstract

The present invention relates to the discovery of protein—protein interactions that are involved in the pathogenesis of neurodegenerative disorders, including Alzheimer's disease (AD). Thus, the present invention is directed to complexes of these proteins and/or their fragments, antibodies to the complexes, diagnosis of neurodegenerative disorders (including diagnosis of a predisposition to and diagnosis of the existence of the disorder), drug screening for agents which modulate the interaction of proteins described herein, and identification of additional proteins in the pathway common to the proteins described herein.


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