The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 25, 2003
Filed:
Jul. 06, 1995
Applicant:
Inventors:
Robert E. Jordan, Malvern, PA (US);
Carrie Lynne Wagner, Malvern, PA (US);
David M. Knight, Berwyn, PA (US);
Assignee:
Centocor, Inc., Malvern, PA (US);
Primary Examiner:
Int. Cl.
CPC ...
A61K 3/817 ; A61K 3/9395 ; C07K 1/4435 ; C07K 1/646 ;
U.S. Cl.
CPC ...
A61K 3/817 ; A61K 3/9395 ; C07K 1/4435 ; C07K 1/646 ;
Abstract
Reduced-immunogenic fusion compounds are disclosed. The fusion compounds of the invention comprise immunogenic compounds linked to auto-antigenic sequences which render the compound less immunogenic. In addition, a method of reducing the immunogenicity of an immunogenic compound is disclosed. The method comprises linking an auto-antigenic sequence to an otherwise immunogenic compound. Recombinant nucleotide sequences encoding auto-antigenic sequences are also disclosed.