The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 18, 2003
Filed:
Apr. 15, 2002
Richard Haynes, Clear Water Bay, Kowloon, Hong Kong, CN;
Ho-Wai Chan, New Territories, Hong Kong, CN;
Wai-Lun Lam, Kowloon, Hong Kong, CN;
Hing-Wo Tsang, Sha Tin, New Territories, Hong Kong, CN;
Wen-Luan Hsiao, Kowloon, Hong Kong, CN;
Hans-Georg Lerchen, B-51375 Leverkusen, DE;
Jörg Baumgarten, D-42115 Wuppertal, DE;
Other;
Abstract
This invention relates to compounds containing a trioxane moiety, especially certain artemisinin derivatives, which have cytotoxic and antitumour activity and their use in the treatment of cancer. Some of these compounds comprise a ligand which is capable of binding to a nucleic acid and a group containing a trioxane moiety which is capable of acting as source of free radicals which are capable of chemically interacting with a nucleic acid. Processes for the preparation of such compounds and pharmaceutical compositions containing such compounds are also provided.