The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 18, 2003
Filed:
Aug. 06, 2002
Elizabeth Janet Pease, Macclesfield, GB;
Gloria Anne Breault, Macclesfield, GB;
Emma Jane Williams, Macclesfield, GB;
Robert Hugh Bradbury, Macclesfield, GB;
Jeffrey James Morris, Macclesfield, GB;
AstraZeneca AB, Sodertalje, SE;
Abstract
Pyrimidine derivatives of the formula (I), wherein: Q and Q are independently selected from aryl or carbon linked heteroaryl optionally substituted as defined within; and one or both Q and Q are substituted on a ring carbon by one substituent of the formula (Ia) or (Ia′), wherein: Y, Z, n, m Q , G, R , are as defined within; and pharmaceutically acceptable salts and in in vivo hydrolysable esters thereof are described. Processes for their manufacture, pharmaceutical compositions and their use as cyclin-dependent serine/threonine kinase (CDK) and focal adhesion kinase (FAK) inhibitors are also described.