The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 18, 2003
Filed:
Jan. 14, 2000
Applicant:
Inventors:
Rosalyn D. Blumenthal, Belleville, NJ (US);
Walter Lew, Caldwell, NJ (US);
Malik Juweid, Bloomfield, NJ (US);
Rita Alisauskas, Hopatcong, NJ (US);
Zhiliang Ying, East Brunswick, NJ (US);
David M. Goldenberg, Mendham, NJ (US);
Assignee:
Center for Molecular Medicine and Immunology, Belleville, NJ (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 3/353 ; G01N 3/3567 ; C07K 1/624 ;
U.S. Cl.
CPC ...
G01N 3/353 ; G01N 3/3567 ; C07K 1/624 ;
Abstract
The invention provides kits and methods for evaluating the myelosuppressive state of a patient. These methods and kits provide a useful adjunct for cytotoxic and myelosuppressive therapies. By establishing threshold levels of certain cytokines as a surrogate for myelosuppression, treatment protocols can be optimized to reduce myelotoxicity, while maximizing effective dose.