The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 11, 2003

Filed:

May. 18, 1995
Applicant:
Inventors:

Michael R. Myers, Reading, PA (US);

Alfred P. Spada, Lansdale, PA (US);

Martin P. Maguire, Mont Clare, PA (US);

Paul E. Persons, King of Prussia, PA (US);

Asher Zilberstein, Broomall, PA (US);

Chin-Yi Jenny Hsu, West Chester, PA (US);

Susan E. Johnson, Upper Darby, PA (US);

Assignee:

Aventis Pharmaceuticals Inc., Bridgewater, NJ (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A01N 4/354 ; C07D / ;
U.S. Cl.
CPC ...
A01N 4/354 ; C07D / ;
Abstract

This invention relates to the modulation and/or inhibition of cell signaling, cell proliferation, cell inflammatory response, the control of abnormal cell growth and cell reproduction. More specifically, this invention relates to the use of mono- and/or bicyclic aryl or heteroaryl quinazoline compounds in inhibiting cell proliferation, including compounds which are useful protein tyrosine kinase (PTK) inhibitors. The method of treating cell proliferation and/or differentiation or mediator release using said quinazoline compounds and their use in pharmaceutical compositions is described.


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