The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 11, 2003

Filed:

Sep. 24, 2002
Applicant:
Inventors:

Jose Maria Fiandor, Madrid, ES;

Sophie Huss, Madrid, ES;

Assignee:

Glaxo Wellcome S.A., Madrid, ES;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 3/15377 ; A61P 3/100 ; C07D / ; C07D / ;
U.S. Cl.
CPC ...
A61K 3/15377 ; A61P 3/100 ; C07D / ; C07D / ;
Abstract

A compound of general formula (I) and physiologically acceptable salts wherein R represents phthalidyl, (2-oxo-5-methyl-1,3-diox-olen-4-yl)methyl or the group CHR OCO(O)pR wherein R is hydrogen or C alcyl, p is zero or I, R is C alkly, C cycloalyl (optionally substituted by C alkyl or carboxyl), C alkyl substituted by C alkoxy or carboxy), C alkyl substituted by one or more groups selected from amino, (C alkylamino di(C alkyl)amino or carboxyl, phenyl (optionally substituted by carboxyl or aminoalkyl, C alkylaminoalkyl or di(C alkyl)aminoalcyl, or R is a 5-8 membered heterocyclic group containing 1 or 2 heteroatoms selected from oxygen or nitrogen, processes for their preparation, pharmaceutical compositions containing them and their use in medicine.


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