The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 04, 2003

Filed:

Oct. 02, 2002
Applicant:
Inventors:

Fukushi Hirayama, Tsukuba, JP;

Hiroyuki Koshio, Tsukuba, JP;

Tsukasa Ishihara, Tsukuba, JP;

Norio Seki, Tsukuba, JP;

Shunichiro Hachiya, Tsukuba, JP;

Keizo Sugasawa, Tsukuba, JP;

Ryota Shiraki, Tsukuba, JP;

Yuji Koga, Tsukuba, JP;

Yuzo Matsumoto, Tsukuba, JP;

Takeshi Shigenaga, Tsukuba, JP;

Souichirou Kawazoe, Tsukuba, JP;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 3/155 ; A61P 7/02 ; C07D / ; C07D / ;
U.S. Cl.
CPC ...
A61K 3/155 ; A61P 7/02 ; C07D / ; C07D / ;
Abstract

To provide a compound which has an anticoagulation action based upon inhibition of activated blood coagulation factor X and is useful as an anticoagulant or an agent for prevention and treatment of diseases caused by thrombus or embolus. A diazepan derivative such as 4-[(3-carbamimidoylphenylamino)methyl]-3-[4-(4-METHYL-1,4-diazepan-1-yl)benzoylamino]benzoic acid and 3-hydroxy-4′-methoxy-2-{[4-(4-methyl-1,4-diazepan-1-yl)benzoyl]amino}benzanilide or a salt thereof is an effective ingredient.


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