The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Nov. 04, 2003

Filed:

Mar. 30, 1998
Applicant:
Inventors:

Peter Andersen, Brønshøj, DK;

Rikke Nielsen, Frederiksberg, DK;

Thomas Oettinger, Hellerup, DK;

Peter Birk Rasmussen, Københaven, DK;

Ida Rosenkrands, Københaven, DK;

Karin Weldingh, Københaven, DK;

Walter Florio, Frederiksberg, DK;

Assignee:

Statens Serum Institut, Copenhagen, DK;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 3/902 ; A61K 3/940 ; A61K 3/904 ; C12N 1/12 ; C12M 1/34 ;
U.S. Cl.
CPC ...
A61K 3/902 ; A61K 3/940 ; A61K 3/904 ; C12N 1/12 ; C12M 1/34 ;
Abstract

The present invention is based on the identification and characterization of a number of derived novel proteins and protein fragments (SEQ ID NOs: 2, 4, 6, 8, 10, 12, 14, 16, 17-23, 42, 48, 50, 52, 54, 56, 58, 60, 62, 64, 66, 68, 70, 72-86, 88, 90, 92, 94, 141, 143, 145, 147, 149, 151, 153, and 168-171). The invention is directed to the polypeptides and immunologically active fragments thereof, the genes encoding them, immunological compositions such as vaccines and skin test reagents containing the polypeptides. Another part of the invention is based on the surprising discovery that fusions between ESAT-6 and MPT59 are superior immunogens compared to each of the unfused proteins, respectively.


Find Patent Forward Citations

Loading…