The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Nov. 04, 2003
Filed:
Jun. 01, 2001
Applicant:
Inventors:
Narasimha M. Vemuri, West Malling, GB;
Andrew B. Brown, West Malling, GB;
Jean-Rene Authelin, Saint Germain les Arpajon, FR;
Patrik Hosek, Kronberg im Taunus, DE;
Assignee:
Aventis Pharma Limited, West-Malling, GB;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
B02C 1/906 ; B02C 1/912 ;
U.S. Cl.
CPC ...
B02C 1/906 ; B02C 1/912 ;
Abstract
The invention is an improved method of generating fine medicament powders suitable for inhalation. A fluid energy mill is used with conventional milling fluids such as air or nitrogen. The milling fluid is treated to have a controlled relative humidity of between 30% and 70%. This produces a fine medicament powder with a median particle size below 10 micrometer but with little or no amorphous content generated during milling. Scale formation in the mill chamber is also greatly reduced.