The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 28, 2003

Filed:

Dec. 03, 1998
Applicant:
Inventors:

Jer-Kang Chen, Palo Alto, CA (US);

Claudia Chiesa, Redwood City, CA (US);

George A. Fry, San Carlos, CA (US);

Vergine C. Furniss, San Mateo, CA (US);

Stephen M. Lambert, Castro Valley, CA (US);

Roger O'Neill, San Carlos, CA (US);

Majid Mehrpouyan, San Jose, CA (US);

Assignee:

PE Corporation (NY), Norwalk, CO (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12M 1/34 ; C12Q 1/68 ; C12P 1/934 ; C07H 2/102 ; C07H 2/104 ;
U.S. Cl.
CPC ...
C12M 1/34 ; C12Q 1/68 ; C12P 1/934 ; C07H 2/102 ; C07H 2/104 ;
Abstract

The present invention provides substrates and apparatuses for efficient, rapid and specific capture, and optimal recovery, of nucleic acids, as well as methods of their use. The substrate is porous in nature and has a capture polynucleotide capable of hybridizing to a target nucleic acid immobilized thereon. Upon flowing a sample containing or suspected of containing the target nucleic acid through the porous substrate, the target nucleic acid is rapidly captured. Following capture, the target nucleic acid can be efficiently recovered for subsequent use.


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