The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 28, 2003

Filed:

Oct. 30, 2000
Applicant:
Inventors:

Nabil El-Tayar, Milton, MA (US);

Michael J. Roberts, Madison, AL (US);

Milton Harris, Huntsville, AL (US);

Wayne Sawlivich, Wilmington, MA (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 3/821 ; A61K 3/174 ; A61K 3/800 ; C07K 1/700 ;
U.S. Cl.
CPC ...
A61K 3/821 ; A61K 3/174 ; A61K 3/800 ; C07K 1/700 ;
Abstract

PEG-IFN-&bgr; conjugates, where a PEG moiety is covalently bound to Cys of human IFN-&bgr;, are produced by a process of site specific PEGylation with a thiol reactive PEGylating agent. A pharmaceutical composition and a method for treating infections, tumors and autoimmune and inflammatory diseases are also provided. The invention further relates to a method for the stepwise attachment of PEG moieties in series to a polypeptide, and more particularly to IFN-&bgr;.


Find Patent Forward Citations

El-Tayar, Nabil. (2003). Polyol-ifn-&bgr;conjugates modified at cys-17 and composition containing same (U.S. Patent No. 6638500). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/6638500

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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