The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 21, 2003

Filed:

Jan. 30, 2002
Applicant:
Inventors:

Rajeshwar Singh, Edmonton, CA;

Nian Zhou, Woodridge, IL (US);

Andhe V. N. Reddy, Edmonton, CA;

George Thomas, Edmonton, CA;

Qizhu Ding, Edmonton, CA;

Jadwiga Kaleta, Edmonton, CA;

Ronald George Micetich, Edmonton, CA;

Mark Whittaker, Abingdon, GB;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D / ; A61K 3/805 ;
U.S. Cl.
CPC ...
C07D / ; A61K 3/805 ;
Abstract

This invention relates to derivatives of alpha-amino acid amides, to pharmaceutical compositions containing such compounds, and to their use in medicine as inhibitors of cysteine proteases, particularly the cathepsins. A compound of formula (I) is described or a pharmaceutically acceptable salt, hydrate or solvate thereof. Pharmaceutically acceptable salts of the compounds of this invention include the sodium, potassium, magnesium, calcium, hydrogen chloride, tartaric acid, succinic acid, fumaric acid and p-toluenesulfonic acid salts.


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