The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 14, 2003

Filed:

Oct. 02, 2001
Applicant:
Inventors:

Kaija Af Ursin, Turku, FI;

Jukka Salmia, Kuusisto, FI;

Heikki Niskanen, Turku, FI;

Pirjo Kortesuo, Parainen, FI;

Mikko Kananen, Kuopio, FI;

Gunilla Örn, Turku, FI;

Juha Kiesvaara, Littoinen, FI;

Assignee:

Orion Corporation, Espoo, FI;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 3/1135 ; A61K 3/138 ; A61K 3/140 ;
U.S. Cl.
CPC ...
A61K 3/1135 ; A61K 3/138 ; A61K 3/140 ;
Abstract

Aqueous compositions of nonsteroidal triphenylethylene antiestrogens for pharmaceutical use comprising as a solubility enhancing agent a pharmaceutically acceptable mono- or dicarboxylic acid having 1-5 carbon atoms, wherein the carbon chain may further contain 1-4 hydroxyl, 1-3 oxo, or one or several halogen a substituents, or a corresponding anion thereof, or methanesulfonic acid or its corresponding anion, in molar excess with respect to the triphenylethylene antiestrogen, optionally together with an organic water miscible co-solvent such as polyethylene glycol (PEG), propylene glycol, ethanol or isopropanol.


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