The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 14, 2003
Filed:
Jul. 06, 1999
Zvi Nevo, Herzliya, IL;
Dror Robinson, Shimson, IL;
Ramot at Tel Aviv University Ltd., Ramot Aviv, IL;
Abstract
A growth support scaffold for cells and tissue is formed of naturally derived connective or skeletal tissue which has been treated for elimination of cellular and cytosolic elements, and modified by cross-linking with hyaluronic acid, proteoglycans, glycosaminoglycans, chondroitin sulfates, heparan sulfates, heparins or dextran sulfates. The scaffold may contain cell adhesive molecules and growth factors, and can be formulated as a malleable prosthesis. A tissue maintenance system is provided containing a chamber having a constant atmosphere which may contain the scaffold impregnated with cells, a medium-containing reservoir, a pump which can be computer controlled for circulating the medium between the chamber and reservoir and may change direction of medium flow every 1 to 3 minutes, and a pressure generator, which can be the pump, for producing rhythmic pulses of pressure such as between 0.5 to 30 atm and frequency of 5-300 per minute.