The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 14, 2003

Filed:

Sep. 10, 1999
Applicant:
Inventors:

Maureen T. Cronin, Los Altos, CA (US);

Garry Miyada, San Jose, CA (US);

Mark Trulson, San Jose, CA (US);

Thomas R. Gingeras, Encinitas, CA (US);

Glenn McGall, Mountain View, CA (US);

Claire Robinson, Palo Alto, CA (US);

Michelle Smedsrud-Oval, Coronado, CA (US);

Assignee:

Affymetrix, Inc., Santa Clara, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/68 ; G01N 1/500 ; C12M 1/00 ; G06F 1/900 ;
U.S. Cl.
CPC ...
C12Q 1/68 ; G01N 1/500 ; C12M 1/00 ; G06F 1/900 ;
Abstract

This invention provides methods of performing nucleic acid hybridization assays on high-density substrate-bound oligonucleotide arrays involving including in the hybridization mixture an isostabilizing agent, a denaturing agent or a renaturation accelerant.


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