The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Oct. 07, 2003
Filed:
Aug. 24, 2000
Applicant:
Inventors:
Jasbir S. Seehra, Lexington, MA (US);
Neelu Kaila, Natick, MA (US);
John C. McKew, Arlington, MA (US);
Jean E. Bemis, Arlington, MA (US);
YiBin Xiang, Acton, MA (US);
Lihren Chen, Cambridge, MA (US);
Assignee:
Genetics Institute LLC, Madison, NJ (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D / ; A61K 3/1404 ; A61K 3/1427 ;
U.S. Cl.
CPC ...
C07D / ; A61K 3/1404 ; A61K 3/1427 ;
Abstract
This invention provides substituted indole and indoline compounds useful in inhibiting phospholipase activity, particularly including cytosolic phospholipase A2 (cPLA2) activity, as well as pharmaceutical compositions containing the compounds and methods of using them to treat various maladies, including pain and inflammatory conditions.