The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Oct. 07, 2003

Filed:

Feb. 24, 2000
Applicant:
Inventors:

Wilfried Bauer, Lampenberg, CH;

Sylvain Cottens, Witterswil, CH;

Dieter Geyl, Heitersheim, DE;

Gabriele Weitz-Schmidt, Bad Krozingen, DE;

Jörg Kallen, Basel, CH;

Ulrich Hommel, Müllheim, DE;

Assignee:

Novartis AG, Basel, CH;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 3/1351 ; A61K 3/14412 ; C07D / ; C07D / ; C07D / ;
U.S. Cl.
CPC ...
A61K 3/1351 ; A61K 3/14412 ; C07D / ; C07D / ; C07D / ;
Abstract

Mevinolin compounds for use in the treatment or prevention of autoimmune diseases, inflammation, ischemia/reperfusion injury and graft rejection. Such compounds bind to the LFA-1 I-domain and thereby inhibit LFA-1/ICAM-1 or LFA-1/ICAM-3 interactions.


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