The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 30, 2003

Filed:

Mar. 20, 2000
Applicant:
Inventors:

David R. Goodlett, Seattle, WA (US);

James E. Bruce, Kennewick, WA (US);

Beate Rist, Seattle, WA (US);

Richard D. Smith, Richland, WA (US);

Ruedi Aebersold, Mercer Island, WA (US);

Assignee:

Other;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
G01N 3/100 ; G01N 1/900 ; G01N 3/348 ; B01D 5/944 ; A61K 3/800 ; C07K 1/400 ; C07K 1/00 ; C07K 1/700 ;
U.S. Cl.
CPC ...
G01N 3/100 ; G01N 1/900 ; G01N 3/348 ; B01D 5/944 ; A61K 3/800 ; C07K 1/400 ; C07K 1/00 ; C07K 1/700 ;
Abstract

The present invention provides methods and reagents for identifying specific masses of compounds in a complex mixture. In particular, the present invention describes an isotope distribution encoded tag (IDEnT) concept wherein the ability to distinguish an analyte encoded with a non-native isotope from those not encoded with the isotope or from those encoded with a different isotope is used for protein identification, enzyme active site identification, peptide sequencing, and the like. Reagents used in the IDEnT strategy consist of a chemical element with a unique isotope distribution not normally found in the analyte class being studied, chemically bonded to, or an integral part of a chemical reagent with a high selectivity of affinity for specific functional group in the analyte.


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