The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Sep. 30, 2003

Filed:

Aug. 13, 2001
Applicant:
Inventors:

Gary Maurice Dull, Lewisville, NC (US);

Erin E. Reich, Nashville, TN (US);

Jared Miller Wagner, Stillwater, OK (US);

Balwinder Singh Bhatti, Winston-Salem, NC (US);

Michael B. Consilvio, Potomac, MD (US);

Assignee:

Targacept, Inc., Winston-Salem, NC (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 3/144 ; C07D / ; C07D / ;
U.S. Cl.
CPC ...
A61K 3/144 ; C07D / ; C07D / ;
Abstract

Patients susceptible to or suffering from conditions and disorders, such as central nervous system disorders, are treated by administering to a patient in need thereof aryloxyalkylamines and arylthioalkylamines, including pyridyloxyl-alkylamines, phenoxyalkylamines, pyridylthiolalkylamines and phenylthio-alkylamines. Exemplary compounds include (2-(5-bromo(3-pyridylthio))-ethyl)methylamine, (2-(5-bromo(3-pyridylthio))isopropyl)methylamine, (2-(5-bromo(3-pyridylthio))propyl)methylamine, (3-(5-bromo(3-pyridylthio))-propyl)methylamine, 3-((3S)-3-pyrrolidinyloxy)pyridine, 3-(4-piperidinyloxy)pyridine, 3-(1-methyl-4-piperidinyloxy)pyridine, (3-benzo&lsqb;3,4-d&rsqb;1,3-dioxolan-5-yloxypropyl)methylamine, and methyl(3-tricyclo&lsqb;7.3.1.0<5,13>&rsqb;tridec-2-yloxypropyl)amine.


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