The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 23, 2003
Filed:
Jul. 09, 2001
Applicant:
Inventors:
Tae Gwan Park, Taejon, KR;
Hyuk Sang Yoo, Taejon, KR;
Assignee:
Korea Advanced Institute of Science and Technology, Taejon, KR;
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 4/748 ; A61K 3/174 ; A61K 3/1785 ; A61K 9/14 ;
U.S. Cl.
CPC ...
A61K 4/748 ; A61K 3/174 ; A61K 3/1785 ; A61K 9/14 ;
Abstract
The present invention relates to a process of preparing a sustained release micelle by copolymerizing a biodegradable polyester hydrophobic polymer and a hydrophilic polyethylene glycol (PEG) to obtain a block copolymer, reacting the block copolymer with a linker to the hydroxyl group of the block copolymer and conjugating the linker-bound block copolymer to a drug to obtain a micelle monomer, and dispersing the micelle monomer an aqueous solution. The drug-micelle conjugate of the present invention has practical application in anticancer therapy.