The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 09, 2003
Filed:
May. 24, 1999
Applicant:
Inventors:
Munehiro Noda, Osaka, JP;
Akinori Sumi, Osaka, JP;
Takao Ohmura, Osaka, JP;
Kazumasa Yokoyama, Osaka, JP;
Assignee:
Mitsubishi Pharma Corporation, Tokyo, JP;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12P 2/100 ; C12P 2/102 ; C07K 1/4765 ; C07K 1/14 ; C07K 1/36 ;
U.S. Cl.
CPC ...
C12P 2/100 ; C12P 2/102 ; C07K 1/4765 ; C07K 1/14 ; C07K 1/36 ;
Abstract
The invention provides a process for purifying recombinant human serum albumin (rHSA) by heating a-culture medium containing rHSA and the rHSA-producing host cells, feeding said heated solution upwardly into a fluidized bed in which adsorbent particles are suspended to effect contacting with the adsorbent particles and then recovering the adsorbed fraction containing the rHSA, and a composition comprising rHSA which shows a A350/A280 ratio of below 0.015, when formulated into a 25% solution of said albumin.