The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 02, 2003
Filed:
Mar. 27, 2001
Jean-Pierre Robin, Le Mans, FR;
Julie Blanchard, Le Mans, FR;
Sylvie Cavoleau, Angers, FR;
Ludovic Chauviat, Le Mans, FR;
Sandra Charbonnel, Angers, FR;
Robert Dhal, Pruillé le Chétif, FR;
Gilles Dujardin, Rouillon, FR;
Florence Fournier, Le Mans, FR;
Chrystelle Gilet, Le Mans, FR;
Laurent Girodier, Le Mans, FR;
Laurence Mevelec, Louvier, FR;
Sandrine Poutot, Le Mans, FR;
Sylvie Rouaud, Le Mans, FR;
Oncopharm Corporation, Houston, TX (US);
Abstract
The present invention concerns a new general process for asymetric hemisynthesis of harringtonines and their analogs, that are alcaloids used in chimiotherapy. This process comprises direct esterification of a natural cephalotaxine with an acylating compound constituted of a side chain precursor which backbone and fonctionalization are entirely preformed.