The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 02, 2003
Filed:
Jun. 06, 2000
Applicant:
Inventors:
Kandasamy Ramasamy, Laguna Hills, CA (US);
Rajanikanth Bandaru, Irvine, CA (US);
Devron Averett, Irvine, CA (US);
Assignee:
ICN Pharmaceuticals, Inc., Costa Mesa, CA (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07H 7/06 ; C07H 5/04 ;
U.S. Cl.
CPC ...
C07H 7/06 ; C07H 5/04 ;
Abstract
C-nucleosides are synthesized by a method in which a sugar is derivatized in a single step to provide a heterocycle at the C position, and then the heterocycle is aromatized in another single step. In one class of preferred embodiments a cyano sugar is converted into thiocarboxamide, and subsequently condensed to form an azole ring. In a second class of preferred embodiments a cyano sugar is condensed with an amino acid to provide the azole ring. In a third class of preferred embodiments a halo sugar is condensed with a preformed heterocycle to provide the azole ring.