The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Sep. 02, 2003
Filed:
Apr. 21, 2000
Applicant:
Inventors:
Raymond A. Firestone, Stamford, CT (US);
Wolfgang J. Rettig, Biberach, DE;
Martin Lenter, Ulm, DE;
Stefan Peters, Ingelheim, DE;
Pilar Garin-Chesa, Biberach, DE;
Juergen Mack, Biberach, DE;
Dietmar Leipert, Ingelheim, DE;
John E. Park, Biberach, DE;
Leila A. Telan, Somerville, MA (US);
Assignee:
Other;
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07K 5/08 ;
U.S. Cl.
CPC ...
C07K 5/08 ;
Abstract
The invention relates to a prodrug that is capable of being converted into a drug by the catalytic action of human fibroblast activation protein (FAP&agr;), said prodrug having a cleavage site which is recognised by FAP&agr;, and said drug being cytotoxic or cytostatic under physiological conditions.