The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 26, 2003

Filed:

Nov. 13, 2001
Applicant:
Inventors:

Yong Sik Youn, Yongin-shi, KR;

Myung Xik Xiang, Yongin-shi, KR;

Byoung Chol Suh, Anyang-shi, KR;

Jong Hoon Kim, Kwachun-shi, KR;

Kwang Hyuk Lee, Kyungkee-do, KR;

Eui Kyung Kim, Seoul, KR;

Jae Kyu Shin, Anyang-shi, KR;

Chung Keun Rhee, Seoul, KR;

Assignee:
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 3/1175 ; A61K 3/1165 ; A61K 3/14409 ; C07C / ; C07D / ;
U.S. Cl.
CPC ...
A61K 3/1175 ; A61K 3/1165 ; A61K 3/14409 ; C07C / ; C07D / ;
Abstract

The present invention provides novel cathecol hydrazone derivatives of formula (I) or pharmaceutically acceptable salts thereof, wherein R is C alkyl or C cycloalkyl; R is hydrogen, hydroxy, C alkyl or —CH CH C(═O)NH ; R and R are independently hydrogen, C alkyl, —C(═X)—R , or 2-, 3- or 4-pyridyl, prymidyl or phenyl substituted with one or two selected from a group consisting of halogen, C alkoxy, nitro, trifluoromethyl, C alkyl and carboxyl, or R and R are directly bonded by C containing oxygen, sulfur or nitrogen to form a heterocyclic ring, X is oxygen, sulfur or NH and R is C alkyl, —NHR , CONH or 2-, 3- or 4-pyridyl, prymidyl or phenyl substituted with one selected from a group consisting of halogen, C alkoxy, nitrile, trifluoromethyl, C alkyl and carboxyl, and R is hydrogen, hydroxy, NH , C alkoxy, C alkyl, pyridyl or phenyl.


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