The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 26, 2003

Filed:

Jul. 08, 1999
Applicant:
Inventors:

John Wahren, Djursholm, SE;

Bo-Lennart Johansson, Uttran, SE;

Hans Jörnvall, Stockholm, SE;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 3/816 ; A61K 3/810 ; A61K 3/808 ;
U.S. Cl.
CPC ...
A61K 3/816 ; A61K 3/810 ; A61K 3/808 ;
Abstract

The invention features peptides that are fragments of the human insulin C-peptide, which peptides include the sequence ELGGGPGAG or a fragment thereof, or the sequence EGSLQ or a fragment thereof. The peptides have the ability to stimulate Na K ATPase activity. Also provided are biomimetic organic compounds exhibiting activation of Na K ATPase activity and/or cellular binding to renal tubule cells and fibroblasts. Such peptides and compounds are useful in combating diabetes and diabetic complications, or for stimulating Na K ATPase activity.


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