The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 26, 2003

Filed:

Jun. 13, 2000
Applicant:
Inventors:

Roger J. Davis, Princeton, MA (US);

Alan Whitmarsh, Shrewsbury, MA (US);

Cathy Tournier, Worcester, MA (US);

Assignee:

University of Massachusetts, Boston, MA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 9/12 ; C12N 1/554 ;
U.S. Cl.
CPC ...
C12N 9/12 ; C12N 1/554 ;
Abstract

Disclosed are human mitogen-activated (MAP) kinase kinase isoforms (MKKs). MKKs mediate unique signal transduction pathways that activate human MAP kinases p38 and JNK, which result in activation of other factors, including activating transcription factor-2 (ATF2) and c-Jun. The pathways are activated by a number of factors, including cytokines and environmental stress. Methods are provided for identifying reagents that modulate MKK function or activity and for the use of such reagents in the treatment of MKK-mediated disorders.


Find Patent Forward Citations

Davis, Roger. (2003). Cytokine-, stress-, and oncoprotein-activated human protein kinase kinases (U.S. Patent No. 6610523). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/6610523

Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile

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