The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 19, 2003

Filed:

May. 07, 2001
Applicant:
Inventors:

Noel John De Souza, Mumbai, IN;

Mahesh Vithalbhai Patel, Aurangabad, IN;

Shiv Kumar Agarwal, Aurangabad, IN;

Shirkant V Gupte, Aurangabad, IN;

Dilip J Upadhyay, Mumbai, IN;

Satish B Bhawsar, Aurangabad, IN;

Mohammad A Jafri, Uttar Pradesh, IN;

Assignee:

Wockhardt Limited, Mumbai, IN;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 3/14375 ; A61P 3/104 ; C07D / ;
U.S. Cl.
CPC ...
A61K 3/14375 ; A61P 3/104 ; C07D / ;
Abstract

The present invention relates to optically pure 8-(substituted piperidino)-benzo[i,j]quinolizines, their isomers, derivatives, salts, pseudopolymorphs, polymorphs prodrugs and hydrates thereof, to processes for their preparation, and to pharmaceutical compositions comprising 8-(substituted piperidino)-benzo[i,j]quinolizines their isomers, derivatives, salts, pseudopolymorphs, polymorphs and hydrates thereof. These compounds and compositions possess potent activity in treating local and systemic infections, particularly infections caused by sensitive and resistant Gram-positive organism infections, Gram-negative organism infections, mycobacterial infections and nosocomial pathogens, and particularly those belonging to the staphylococcus, streptococcus and enterococcus groups. Methods for treating the diseases and disorders arising from the foregoing infections in humans and animals are described by administering the compounds of the invention to said humans and animals.


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