The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 19, 2003
Filed:
Sep. 01, 2000
Applicant:
Inventors:
Jeffrey M. Besterman, Baie d'Urfe, CA;
Jubrail Rahil, Dollard des Ormeaux, CA;
Rex Pratt, Portland, CT (US);
Assignee:
MethylGene, Inc., St. Laurent, CA;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 3/1661 ; A61K 3/1662 ; C07F 9/02 ;
U.S. Cl.
CPC ...
A61K 3/1661 ; A61K 3/1662 ; C07F 9/02 ;
Abstract
The invention provides novel &bgr;-lactamase inhibitors, which are structurally unrelated to the natural product and semi-synthetic &bgr;-lactamase inhibitors presently available, and which do not possess &bgr;-lactam pharmacophore. These new inhibitors are fully synthetic, allowing ready access to a wide variety of structurally related analogs. Certain embodiments of these new inhibitors also bind bacterial DD-peptidases, thus potentially acting both as &bgr;-lactamase inhibitors and as antibiotics.