The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 12, 2003

Filed:

Oct. 09, 1998
Applicant:
Inventors:

Cameron Skinner, Edmonton, CA;

Thompson Tang, Edmonton, CA;

D. Jed Harrison, Edmonton, CA;

Nicolas Bings, Bloomington, IN (US);

Can Wang, Edmonton, CA;

Gregor Ocvirk, Edmonton, CA;

Jianjun Li, Hull, CA;

Pierre Thibault, Aylmer, CA;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 3/300 ; G01N 2/727 ; B01D 5/944 ;
U.S. Cl.
CPC ...
G01N 3/300 ; G01N 2/727 ; B01D 5/944 ;
Abstract

A method is provided for joining a microchip device to a capillary tube. The microchip device has a capillary channel opening onto an edge surface of the device. A short hole is drilled into the edge surface, aligned with the capillary channel. The drilling is done with a flat bottom, preferably by a two-step drilling process. Then, the end of the capillary can be inserted into the hole so that its end is substantially flush with the flat bottom of the hole, thereby eliminating dead volume. Testing has shown that this connection provides very little band broadening of samples transported through the capillary channel into the capillary tube. The tip of the capillary tube can be tapered, so that it is suitable for use as an electrospray source for a mass spectrometer.


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