The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Aug. 12, 2003
Filed:
Aug. 17, 1999
Applicant:
Inventor:
Bharat B. Aggarwal, Houston, TX (US);
Assignee:
Research Development Foundation, Carson City, NV (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 3/9395 ;
U.S. Cl.
CPC ...
A61K 3/9395 ;
Abstract
The present invention provides methods for the therapeutic application of TRANK, a novel cytokine. TRANK is secreted by cells and activates NF-&kgr;B, c-Jun N-terminal kinase (JNK) and downstream gene products. Provided is a method of inhibiting NF-&kgr;B activation in an individual in need of such treatment, comprising the step of administering an effective dose of an anti-TRANK antibody to said individual.