The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 05, 2003

Filed:

Aug. 20, 2002
Applicant:
Inventors:

Ramon Berenguer Maimo, Barcelona, ES;

Julio Campon Pardo, Barcelona, ES;

Laura Coppi, Barcelona, ES;

Assignee:
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 3/14439 ; C07D / ;
U.S. Cl.
CPC ...
A61K 3/14439 ; C07D / ;
Abstract

The present invention relates to a procedure for the oxidation of a thioether group to a sulfoxide group, with aqueous sodium percarbonate in the presence of a molybdenum salt as a catalyst. The procedure is of application to oxidize the thioether group of a compound (I), where R is a C -C alkyl, a halogenated C -C alkyl, or —(CH ) —OR , where n is an integer between 1 and 6 and R is H or a C -C alkyl; R , R , R , R , R and R , independently form each other represent H, a C -C alkyl, or C -C alkoxy; and R is H, a C -C alkyl, a C -C alkoxy or a C -C fluorinated alkoxy, in order to obtain the sulfinyl derivative (II).


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