The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Aug. 05, 2003

Filed:

Feb. 23, 2001
Applicant:
Inventors:

Ilan Ziv, Kfar-Sava, IL;

Anat Shirvan, Herzilya, IL;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 3/817 ; C07K 1/447 ; G01N 3/368 ;
U.S. Cl.
CPC ...
A61K 3/817 ; C07K 1/447 ; G01N 3/368 ;
Abstract

The present invention relates to an NST300 compound of general formula (I): comprising the following components: X1—[(X3)a/(X4)b] in which X1 represents a fatty acid or prenyl group; and X3 represents a domain of positively charged amino acids; and X4 represents a domain containing aromatic amino acids; and a stands for an integer of 1-8; and b stands for an integer of 1-8. The invention relates also to pharmaceutical compositions comprising a compound of general formula (I), the use of the compound and of the pharmaceutical composition in the preparation of a medicament and in methods for the treatment or prevention of prothrombic states in disorders which are associated with excessive procoagulant activity, initiated or propagated by CMLA loss. The invention relates also to the use of the compound and of the pharmaceutical composition for the diagnosis of CMLA loss; as a targeting agent; as targeting drugs to tissues inflicted by CMLA loss; and for basic research in fields of research in which CMLA loss takes place both in vitro and in vivo.


Find Patent Forward Citations

Loading…