The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 29, 2003
Filed:
Mar. 16, 2001
Paul A. Averback, Beaconsfield, CA;
Celine Dupuis, Beaconsfield, CA;
Nymox Corporation, St. Laurent, CA;
Abstract
Disclosed is a method of detecting amyloid-containing deposits in a mammal without administering exogenous chemicals such as fluorophores or chromophores. The method includes subjecting tissue of a mammal, preferably tissue of a mammal suspected of having at least one form of amyloidosis to autofluorescence-initiation, preferably by subjecting the tissue to at least excitation incident radiation from a light source having a wavelength of light within the range of from about 360 to about 370 nm, and more preferably to illumination incident radiation from a light source having wavelengths in the visible spectrum, to produce an emitted light signal beam and a reflected light signal beam. The method also preferably includes detecting the presence of emitted light having a wavelength of from about 400 nm to about 460 nm. The method can be used to diagnose amyloidosis in living mammals using relatively non-invasive imaging apparatus, and it can be used to monitor the efficacy of treatment, or screen effective treatments for amyloidosis.