The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 29, 2003

Filed:

Sep. 06, 2001
Applicant:
Inventors:

Louise Robinson, San Carlos, CA (US);

Prasad V. V. S. V. Manchem, South San Francisco, CA (US);

Nicolas Cairns, Burlingame, CA (US);

Steven R. Schow, Redwood Shores, CA (US);

Assignee:

Telik, Inc., Palo Alto, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07C / ; A61K 3/1185 ;
U.S. Cl.
CPC ...
C07C / ; A61K 3/1185 ;
Abstract

Compounds of Formula I, and pharmaceutical compositions containing these compounds, activate the insulin receptor kinase, which leads to an increased sensitivity to insulin and an increase in glucose uptake, and are therefore useful for the treatment of animals, especially humans, with hyperglycemia, especially for the treatment of type 2 diabetes. Processes for preparation of the compounds, and their use in assays, are also disclosed.


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