The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 29, 2003
Filed:
Feb. 01, 2000
Daniel Brown, Cambridge, GB;
David Loakes, Letchworth, GB;
David Williams, Sheffield, GB;
Fergal Hill, Cambridge, GB;
Shiv Kumar, Belle Mead, OH (US);
Satyam Nampalli, Belle Mead, OH (US);
Mark McDougall, Bethlehem, PA (US);
Alan Hamilton, Amersham, GB;
Clifford Smith, Tring, GB;
Adrian Christopher Simmonds, Amersham, GB;
William Jonathan Cummins, Tring, GB;
Patrick Finn, Belle Mead, NJ (US);
Amersham Pharmacia Biotech UK Limited, Buckinghamshire, GB;
Abstract
Nucleoside analogues have structure (2) wherein Q is H or a sugar moiety or sugar analogue or a modified sugar or a nucleic backbone or backbone analogue, W is an alkylene or alkenylene chain of 0-5 carbon atoms, any of which may carry a substituent R , X is O or N or NR or CR , X′ is O or S or N, provided that when X′ is O or S, then X is C, Y is CH or N, R is NH or SMe or SO Me or NHNH , each of R and R is independently H or F or alkyl or alkenyl or aryl or acyl or a reporter moiety, R is independently H or alkyl or alkenyl or aryl or acyl or a reporter moiety, and R is H or ═O or F or alkyl or aryl or a reporter moiety.