The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 22, 2003
Filed:
Jan. 22, 2002
Applicant:
Inventors:
Paul O. Zamora, Gaithersburg, MD (US);
Ray Tsang, Salt Lake City, UT (US);
Shigemasa Osaki, Sandy, UT (US);
Assignee:
BioSurface Engineering Technologies, Inc., College Park, MD (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 3/170 ; A61K 3/1727 ; A61M 5/32 ; B01J 1/300 ; C08B 3/710 ;
U.S. Cl.
CPC ...
A61K 3/170 ; A61K 3/1727 ; A61M 5/32 ; B01J 1/300 ; C08B 3/710 ;
Abstract
A nucleic acid coating composition including a polyanion bound, directly or through one or more intermediates, to a medical device surface, with a condensate comprising a polycation and nucleic acid bound to the polyanion, devices incorporating such coating compositions, and methods for making. In one embodiment, a silyl-heparin complex is provided, bound to a medical device surface by hydrophobic interaction with the silyl moiety, with a polycation and nucleic acid condensate bound to the heparin by electrostatic interaction.