The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jul. 22, 2003
Filed:
Sep. 22, 1999
Applicant:
Inventors:
Michael E. Jolley, Round Lake, IL (US);
Klaus H. Nielsen, Richard Ontario, CA;
Assignee:
Other;
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
G01N 3/3533 ; C07G 1/700 ; C07H 1/00 ;
U.S. Cl.
CPC ...
G01N 3/3533 ; C07G 1/700 ; C07H 1/00 ;
Abstract
In a homogeneous immunoassay, fluorophore-conjugated lipopolysaccharide derived bacterial antigens are reacted with antibodies specific for the antigens. Quantitative detection of the formation of an immune complex is obtained by measuring the change in fluorescence polarization after complex formation. The reaction occurs quickly (less than two minutes to equilibrium), and involves the addition of only one reagent to a diluted serum specimen. The absence of a solid phase separation step eliminates false positive results and increases throughput.