The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 22, 2003

Filed:

Apr. 16, 2001
Applicant:
Inventors:

Joseph T. Bruder, Ijamsville, MD (US);

Imre Kovesdi, Rockville, MD (US);

Assignee:

GenVec, Inc., Gaithersburg, MD (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 3/500 ; A61K 4/800 ; A61K 3/9235 ; C12N 1/563 ;
U.S. Cl.
CPC ...
A61K 3/500 ; A61K 4/800 ; A61K 3/9235 ; C12N 1/563 ;
Abstract

The present invention provides methods for administering an adenoviral gene transfer vector comprising an exogenous gene to an animal. One method involves utilizing systemic neutralizing antibodies to neutralize the adenoviral gene transfer vector outside a targeted muscle. Another method involves the repeat administration of an adenoviral gene transfer vector to a skeletal muscle.


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