The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jul. 15, 2003

Filed:

Apr. 12, 2000
Applicant:
Inventors:

Scott W. Altmann, Fanwood, NJ (US);

Duane A. Burnett, Bernardsville, NJ (US);

Harry R. Davis, Jr., Berkeley Heights, NJ (US);

Michael P. Graziano, Scotch Plains, NJ (US);

Maureen Laverty, Metuchen, NJ (US);

Xiaorui Yao, Edison, NJ (US);

Assignee:

Schering Corporation, Kenilworth, NJ (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12Q 1/00 ; C12Q 3/3567 ;
U.S. Cl.
CPC ...
C12Q 1/00 ; C12Q 3/3567 ;
Abstract

The use of azetidinone compounds that are inhibitors of cholesterol absorption as tools for discovering and characterizing proteins involved in trafficking or absorption of cholesterol and/or cholesteryl esters in biological systems is presented. These compounds can serve as tools for competitive binding assays to discover and characterize other chemical agents useful as cholesterol absorption inhibitors. New compounds of the present invention are also highly efficacious inhibitors of cholesterol absorption.


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